Neuropathology Core - South Texas Alzheimer's Disease Research Center

Aims
1. Access fixed and frozen central nervous system tissues and postmortem skin and cerebrospinal fluid samples through standardized and rapid autopsies of the center’s participants and other clinic and community donors nationwide.
2. Provide data-driven neuropathologic evaluations and diagnoses for all brain donors in accordance with institutional dissection and histology protocols.
3. Manage a state-of-the-art biorepository, including fixed and frozen autopsy tissues, biofluids, DNA/RNA and induced pluripotent stem cells, for the center’s researchers and other external investigators.
4. Contribute to scientific research projects regarding the individual and synergistic effects of neurodegenerative, cerebrovascular and traumatic neuropathologies on brain aging and ante-mortem cognitive and behavior.
5. Assist the Research Education Core by providing neuropathology training, research and educational opportunities to biomedical personnel, scientists, students and the public.